Julie Sherrell lost her grandfather to blood cancer about 10 years ago, and has a friend in remission who was diagnosed with the disease five years ago.

Mrs Sherrell said she chose to lose her locks in the World's Greatest Shave to raise awareness of the disease and to help people who have been diagnosed with the cancer.

"There's so many people affected by blood cancers and I feel like it's one of the ones that's not well-known. There's no symptoms that make it obvious you've got blood cancer," Mrs Sherrell said.

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"The greatest shave not only raises money for research into treatments, an $80 donation can help keep rural families together when relocating to a capital city for urgent treatment.

"Parents no longer have to choose between paying for a nights accommodation they can't really afford or paying for food for the rest of the family for a week."

But the Gunnedah resident isn't phased at the thought of having no hair.

"It'll grow back, and if all else fails I can wear a hat," she said.

The big event is on Saturday, March 14, and the ladies of The Hair Studio Gunnedah have agreed to shave Mrs Sherrell's head.

She is about $400 away from her target of $2000, and encouraged locals to get involved in raising funds for the Leukaemia Foundation.

Locals can donate via the Leukaemia Foundation website at http://my.leukaemiafoundation.org.au/juliesherrell