Many Gunnedah residents were spotted with large packs of toilet paper in their trollies at Gunnedah Woolworths on Wednesday, with shelves looking emptier than usual. Tissues were also in a shorter supply.

Woolworths has put signs on the toilet paper shelves to inform shoppers that there is a four-pack per transaction limit on toilet paper.

The sign says this is "due to higher than usual demand".

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Premier Gladys Berejiklian said the recent escalation in coronavirus cases was concerning, but encouraged people to not panic.

"All of us should take the advice of the health experts, no doubt about it. But we should also go about our business and not panic, and that's the strongest message we can send," Ms Berejiklian said.

"It's really important for us to take a precautionary approach ... we've made sure we've put in place everything we can to contain the spread."

The premier said there were no issues with toilet paper supply in NSW and urged the public to refrain from bulk-buying at supermarkets.

"People should just go about their daily business in terms of the products they purchase, and I don't see a need to [bulk buy] at this stage," she said.

Company Kimberly-Clark, which manufactures toilet paper, is opening up its manufacturing lines in South Australia to deal with shortages.

Coles has been contacted for comment.

Australian Associated Press